Bioinformatics Seminar

The Bioinformatics Seminar is co-sponsored by the Department of Mathematics at the Massachusetts Institute of Technology and the Theory of Computation group at MIT's Computer Science and Artificial Intelligence Laboratory (CSAIL). The seminar series focuses on highlighting areas of research in the field of computational biology. This year, we are hoping to highlight three topics: (1) language models and their uses in biology and biomedicine, (2) ethical and societal issues in biomedical data (e.g. privacy, fairness), and (3) single-cell biology.

Fall 2021

Date Speaker Title Abstract
Sep. 15 Liana Lareau
(University of California, Berkeley)
Identifying cell state associated alternative splicing events and their co-regulation PDF
Sep. 22 Ben Raphael
(Princeton University)
Quantifying Tumor Heterogeneity across Time and Space PDF
Sep. 29 Lenore Cowen
Tufts University
Diffusion-Based Methods for Biological Network Analysis PDF
Oct. 6 Xuegong Zhang
(Tsinghua University)
Toward a Unified Information Framework for Cell Atlas Assembly PDF
Oct. 13 Christina Leslie
(Sloan Kettering Institute)
Advances in predictive models for regulatory genomics PDF
Oct. 20 Jean Fan
(Johns Hopkins University)
Multi-scale computational analysis of spatially resolved transcriptomic imaging data PDF
Oct. 27 Stacey Finley
(University of Southern California)
Mechanistic modeling of immune cell activation in cancer PDF
Nov. 3 Aaron Streets
(University of California, Berkeley)
Single-cell multimodal analysis of thymocyte development reveals drivers of CD4/CD8 lineage commitment PDF
Nov. 10 Nima Aghaeepour
Multiomics Analysis of the Immunome, Transcriptome, Microbiome, Proteome, and Metabolome in Term Pregnancy PDF
Nov. 17 Charlotte Deane
Machine learning for early stage drug discovery PDF
Nov. 24 Janet Thornton
(European Molecular Biology Laboratory)
Computational Enzymology: Towards using knowledge of structure and function to predict enzyme transformations and mechanisms. PDF
Dec. 1 Elodie Ghedin
Shedding light in a dark place: Microbial ecology of the airways in respiratory infections PDF
Dec. 8 Arjun Raj
(University of Pennsylvania)
Emergent cellular ecosystems in melanoma revealed by single cell analysis PDF

Past Terms

A listing of the Bioinformatics Seminar series home pages from prior terms.

Organizers and Information

The Bioinformatics Seminar is hosted by MIT Simons Professor of Mathematics and head of the Computation and Biology group at CSAIL Bonnie Berger. Professor Berger is also Faculty of Harvard-MIT Health Sciences & Technology, Associate Member of the Broad Institute of MIT and Harvard, Faculty of MIT CSB, and Affiliated Faculty of Harvard Medical School.

The seminar is announced weekly via email to members of the seminar's mailing list and to those on CSAIL's event calendar list. It is also posted in the BioWeek calendar.

Bonnie Berger:

Shuvom Sadhuka (TA):

To be added to the seminar's email announcement list or for any questions you have about the seminar, please mail

If you plan to enroll in the associated course, 18.418/HST.504: Topics in Computational Molecular Biology, please contact Professor Berger ( and cc TA Shuvom Sadhuka ( for more information.